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From Hammarlund Lab
Welcome to the Hammarlund Lab
We study the genetics and cell biology of axon regeneration and degeneration using the model organism C. elegans.
Axon plasticity in the nervous system can result from experience, injury, or disease. Changes in axon structure can profoundly affect the connectivity and function of the nervous system. How is axon plasticity regulated and executed?
We have developed a suite of genetic tools to initiate and monitor regeneration and degeneration, two fundamental forms of axon plasticity. We have used these tools to identify genes required for regeneration and degeneration. We also use laser surgery to sever individual axons. Because C. elegans is transparent and has a simple nervous system, we can observe regeneration and degeneration in vivo. Our long-term goal is to understand and control plasticity at the molecular level.
News
2009
October 6: Welcome postdoc Alexandra Byrne
June 24-28: International C. elegans Meeting
June 10: "Imaging Axon Regeneration in vivo", Yale Microscopy Workshop
May 18: Welcome back grad student Tyson Edwards
May 7: Welcome back grad student Christopher Firnhaber
April 24: Arnold and Mabel Beckman Foundation Young Investigator Award.
Jan. 22: "Axon regeneration requires a conserved MAP kinase pathway" published in Science. PDF
Jan. 12: Welcome technician Laura Klein
Jan. 7: Welcome rotation student Tyson Edwards
Jan. 5: Welcome rotation student Christopher Firnhaber
2008
Dec. 12: Genetics Department Holiday Party
Dec. 12: Last day of Patrick McMillen's rotation.
Dec. 11: CNNR Open House

